New acetylphenol-based acyl thioureas broaden the scope of drug candidates for urease inhibition: synthesis, in vitro screening and in silico analysis
Urage Zahra, Sumera Zaib, Aamer Saeed, Mujeeb Ur Rehman, Ghulam Shabir, Hashem O. Alsaab, Imtiaz Khan
Topics & Concepts
UreaseIn silicoThioureaDrugPharmacologyChemistryIC50EnzymeIn vitroHelicobacter pyloriBiochemistryBiologyGeneGeneticsOrganic chemistryMicrobial Applications in Construction MaterialsEnzyme function and inhibitionBiochemical and Molecular Research