Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells
Cegui Hu, Wen Qiao, Xiang Li, Zhikun Ning, Jiang Liu, Sumiya Dalangood, Hanjun Li, Xiang Yu, Zhen Zong, Zhenke Wen, Jun Gui
Topics & Concepts
Immune systemSuppressorFGF21BiologyCD8Cell biologyCytotoxic T cellMetabolismImmunologyEndocrinologyBiochemistryFibroblast growth factorCancerGeneticsReceptorIn vitroFibroblast Growth Factor ResearchPhagocytosis and Immune RegulationImmune cells in cancer