Identification of saquinavir as a potent inhibitor of dimeric SARS-CoV2 main protease through MM/GBSA
Martiniano Bello, Alberto Martínez-Muñoz, Irving Balbuena-Rebolledo
Topics & Concepts
DarunavirChemistrySaquinavirDocking (animal)ProteaseIndinavirRaltegravirPharmacologyComputational biologyBiochemistryEnzymeVirologyHuman immunodeficiency virus (HIV)MedicineBiologyNursingViral diseaseAntiretroviral therapySidaViral loadComputational Drug Discovery MethodsSARS-CoV-2 and COVID-19 ResearchEnzyme function and inhibition