The circadian nuclear receptor RORα negatively regulates cerebral ischemia–reperfusion injury and mediates the neuroprotective effects of melatonin
Minhua Zang, Yichao Zhao, Lingchen Gao, Fangyuan Zhong, Zihan Qin, Renyang Tong, Lulu Ai, Lauren Petersen, Yan Yang, Yu Gao, Cansheng Zhu, Jun Pu
Topics & Concepts
MelatoninNeuroprotectionOxidative stressEndocrinologyInternal medicineCircadian rhythmPineal glandReperfusion injuryMelatonin receptorMedicineIschemiaPharmacologyCircadian rhythm and melatoninDietary Effects on HealthAntioxidant Activity and Oxidative Stress