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Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks

Adam J. Rubin, Kevin R. Parker, Ansuman T. Satpathy, Yanyan Qi, Beijing Wu, Alvin J. Ong, Maxwell R. Mumbach, Andrew L. Ji, Daniel Sunwook Kim, Seung Woo Cho, Brian Zarnegar, William J. Greenleaf, Howard Y. Chang, Paul A. Khavari

2018Cell331 citationsDOIOpen Access PDF

Topics & Concepts

BiologyEpigenomicsCRISPRProfiling (computer programming)Computational biologyGene expression profilingGene regulatory networkGeneticsGeneGene expressionDNA methylationComputer scienceOperating systemCRISPR and Genetic EngineeringSingle-cell and spatial transcriptomicsGene Regulatory Network Analysis
Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks | Litcius