Litcius/Paper detail

A scoping review of privacy and utility metrics in medical synthetic data

Bayrem Kaabachi, Jérémie Despraz, Thierry Meurers, Karen Otte, Mehmed Halilovic, Bogdan Kulynych, Fabian Praßer, Jean Louis Raisaro

2025npj Digital Medicine58 citationsDOIOpen Access PDF

Abstract

The use of synthetic data is a promising solution to facilitate the sharing and reuse of health-related data beyond its initial collection while addressing privacy concerns. However, there is still no consensus on a standardized approach for systematically evaluating the privacy and utility of synthetic data, impeding its broader adoption. In this work, we present a comprehensive review and systematization of current methods for evaluating synthetic health-related data, focusing on both privacy and utility aspects. Our findings suggest that there are a variety of methods for assessing the utility of synthetic data, but no consensus on which method is optimal in which scenario. Moreover, we found that most studies included in this review do not evaluate the privacy protection provided by synthetic data, and those that do often significantly underestimate the risks.

Topics & Concepts

Computer scienceVariety (cybernetics)ReuseData sharingSynthetic dataData scienceInformation privacyData collectionHealth dataRisk analysis (engineering)Health careInternet privacyBusinessArtificial intelligenceEngineeringMedicineEconomic growthPathologyEconomicsMathematicsWaste managementAlternative medicineStatisticsPrivacy-Preserving Technologies in DataEthics in Clinical ResearchHealth Systems, Economic Evaluations, Quality of Life