NLRP3 inflammasome-driven IL-1β and IL-18 contribute to lipopolysaccharide-induced septic cardiomyopathy
Kenta Fujimura, Tadayoshi Karasawa, Takanori Komada, Naoya Yamada, Yoshiko Mizushina, Chintogtokh Baatarjav, Takayoshi Matsumura, Kinya Otsu, Norihiko Takeda, Hiroaki Mizukami, Kazuomi Kario, Masafumi Takahashi
Topics & Concepts
InflammasomeLipopolysaccharideInflammationSepsisMedicinePathophysiologyInnate immune systemImmunologyCaspase 1CardiomyopathySystemic inflammatory response syndromeCardiac dysfunctionPyrin domainImmune systemInternal medicineHeart failureInflammasome and immune disordersSepsis Diagnosis and TreatmentAutoimmune and Inflammatory Disorders Research