Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles
Sander A. A. Kooijmans, Stephan Stremersch, Kevin Braeckmans, Stefaan C. De Smedt, An Hendrix, Matthew J. A. Wood, Raymond M. Schiffelers, Koen Raemdonck, Pieter Vader
Topics & Concepts
ElectroporationNucleic acidChemistryBiophysicsLiposomeSmall interfering RNAVesicleDrug carrierDrug deliveryIntracellularCell biologyTransfectionBiochemistryBiologyMembraneOrganic chemistryGeneExtracellular vesicles in diseaseRNA Interference and Gene DeliveryMicroRNA in disease regulation