Direct Construction of Quaternary Carbons from Tertiary Alcohols via Photoredox-Catalyzed Fragmentation oftert-AlkylN-Phthalimidoyl Oxalates
Gregory L. Lackner, Kyle W. Quasdorf, Larry E. Overman
Abstract
A convenient method for the direct construction of quaternary carbons from tertiary alcohols by visible-light photoredox coupling of tert-alkyl N-phthalimidoyl oxalate intermediates with electron-deficient alkenes is reported.
Topics & Concepts
ChemistryAlkylPhotoredox catalysisCatalysisOxalateQuaternaryFragmentation (computing)Quaternary carbonTertiary alcoholsPhotochemistryOrganic chemistryPhotocatalysisEnantioselective synthesisPaleontologyBiologyComputer scienceOperating systemRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsFluorine in Organic Chemistry