A biodegradable covalent organic framework for synergistic tumor therapy
Wenyan Li, Jing-Jing Wan, Jing‐Lan Kan, Bo Wang, Tian Song, Qun Guan, Lele Zhou, Yanan Li, Yu‐Bin Dong
Abstract
ferroptosis is achieved. In this research, the therapeutic efficacy was significantly improved in terms of enhanced combined anti-tumor efficiency and reduced side effects by responding to significant abnormalities such as high concentrations of GSH in the tumor microenvironment (TME).
Topics & Concepts
Covalent bondChemistryCombinatorial chemistryNanotechnologyMaterials scienceOrganic chemistryNanoplatforms for cancer theranosticsCovalent Organic Framework ApplicationsMetal-Organic Frameworks: Synthesis and Applications