Does Sleep Flush Wastes From the Brain?
Anthony L. Komaroff
Abstract
This Viewpoint explains emerging science that suggests sleep activates the meningeal lymphatic and glymphatic systems to flush fluid and waste products out of the brain and discusses associations between disrupted sleep and neurological disease that may be mediated by glymphatic dysfunction.
Topics & Concepts
Glymphatic systemMedicineSleep (system call)Lymphatic systemNeurosciencePathologyCerebrospinal fluidOperating systemComputer scienceBiologyCerebrospinal fluid and hydrocephalusNeuroscience of respiration and sleepNeonatal and fetal brain pathology