International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1–4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions
Xavier Norel, Yukihiko Sugimoto, Gülsev Özen, Heba Abdelazeem, Yasmine Amgoud, Amel Bouhadoun, Wesam Bassiouni, Marie Goepp, Salma Mani, Hasanga D. Manikpurage, Amira Senbel, Dan Longrois, Ákos Heinemann, Chengcan Yao, Lucie H. Clapp
Abstract
, produced during inflammatory conditions in human and rodents. In addition, this comparison of the published results in each tissue and/or pathology should facilitate the choice of the most appropriate model for the future studies.
Topics & Concepts
ProstacyclinReceptorProstaglandin E2 receptorProstaglandinBiologyG protein-coupled receptorPharmacologyEndocrinologyCell biologyInternal medicineMedicineBiochemistryAgonistInflammatory mediators and NSAID effectsEicosanoids and Hypertension PharmacologyEstrogen and related hormone effects