‘Adhesion and release’ nanoparticle-mediated efficient inhibition of platelet activation disrupts endothelial barriers for enhanced drug delivery in tumors
Jinxu Cao, Peng Yang, Pengzhen Wang, Shuting Xu, Yunlong Cheng, Kang Qian, Minjun Xu, Dongyu Sheng, Yixian Li, Yan Wei, Qizhi Zhang
Topics & Concepts
PlateletPlatelet activationDrug deliveryCancer researchIntegrinExtracellular matrixPharmacologyPancreatic cancerPlatelet adhesivenessMaterials scienceCell biologyMedicineChemistryImmunologyCancerBiochemistryBiologyNanotechnologyReceptorInternal medicinePlatelet aggregationInflammatory Biomarkers in Disease PrognosisNanoparticle-Based Drug DeliveryExtracellular vesicles in disease