Differential localization patterns of claudin 10, 16, and 19 in human, mouse, and rat renal tubular epithelia
Caroline Prot‐Bertoye, Camille Griveau, Karsten Skjødt, Lydie Cheval, Gaëlle Brideau, Loïc Lièvre, Elsa Ferrière, Floriane Arbaretaz, Kévin Garbin, Reza Zamani, Niels Marcussen, Lucile Figueres, Tilman Breiderhoff, Dominik Müller, Patrick Bruneval, Pascal Houillier, Henrik Dimke
Abstract
This study used immunohistochemistry and immunofluorescence to investigate the distribution of claudin 10, 16, and 19 in the human, mouse, and rat kidney. The findings showed distinct junctional pathways in both human and rodent kidneys, supporting the existence of different permeation profiles in all species investigated.
Topics & Concepts
ClaudinDifferential (mechanical device)Tight junctionCell biologyBiologyChemistryPhysicsThermodynamicsBarrier Structure and Function StudiesNeurological Disease Mechanisms and TreatmentsNeonatal and fetal brain pathology