A simple and feasible atom-precise biotinylated Cu(<scp>i</scp>) complex for tumor-targeted chemodynamic therapy
Bi Luo, Liguang Chen, Zhao-Guo Hong, Xin You, Fu‐Ping Huang, He‐Dong Bian, Liangliang Zhang, Shulin Zhao
Abstract
A simple and feasible atom-precise biotinylated Cu(<sc>i</sc>) complex, which can catalyze H<sub>2</sub>O<sub>2</sub> overexpressed commonly in the tumor microenvironment to produce ˙OH through a Fenton-like reaction, was prepared and employed as an effective agent for tumor-targeted chemodynamic therapy.
Topics & Concepts
BiotinylationChemistryTumor microenvironmentAtom (system on chip)Combinatorial chemistrySimple (philosophy)Tumor cellsBiophysicsCancer researchComputer scienceBiochemistryBiologyEmbedded systemEpistemologyPhilosophyNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisNanoparticle-Based Drug Delivery