Efficient PD-L1 imaging of murine glioblastoma with FUS-aided immunoPET by leveraging FcRn-antibody interaction
Céline Chevaleyre, Anthony Novell, Nicolas Tournier, Ambre Dauba, Steven G. DuBois, Dimitri Kereselidze, Erwan Selingue, Benoit Jégo, Bernard Maillère, Benoît Larrat, Hervé Nozach, Charles Truillet
Abstract
for immunoPET imaging. FUS-aided BBB/BTB disruption enables quantitative imaging of PD-L1 expression by glioblastoma tumors within the brain.
Topics & Concepts
GlioblastomaBispecific antibodyMonoclonal antibodyCancer researchAntibodyChemistryMedicineImmunologyMonoclonal and Polyclonal Antibodies ResearchCAR-T cell therapy researchAdvanced Biosensing Techniques and Applications