A comparison of the pharmacokinetics and NMDAR antagonism-associated neurotoxicity of ketamine, (2R,6R)-hydroxynorketamine and MK-801
Patrick J. Morris, Richard Burke, Alok Sharma, Daniel C. Lynch, Leslie E. Lemke-Boutcher, Shiny Mathew, Ikram Elayan, Deepa B. Rao, Todd D. Gould, Carlos A. Zarate, Panos Zanos, Ruin Moaddel, Craig J. Thomas
Topics & Concepts
KetamineNeurotoxicityPharmacologyNeuropathologyNMDA receptorMedicineDosingPharmacokineticsAntagonistToxicityMemantineAnesthesiaInternal medicineReceptorDiseaseTreatment of Major DepressionAnesthesia and Neurotoxicity ResearchAnesthesia and Sedative Agents