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A comparison of the pharmacokinetics and NMDAR antagonism-associated neurotoxicity of ketamine, (2R,6R)-hydroxynorketamine and MK-801

Patrick J. Morris, Richard Burke, Alok Sharma, Daniel C. Lynch, Leslie E. Lemke-Boutcher, Shiny Mathew, Ikram Elayan, Deepa B. Rao, Todd D. Gould, Carlos A. Zarate, Panos Zanos, Ruin Moaddel, Craig J. Thomas

2021Neurotoxicology and Teratology28 citationsDOIOpen Access PDF

Topics & Concepts

KetamineNeurotoxicityPharmacologyNeuropathologyNMDA receptorMedicineDosingPharmacokineticsAntagonistToxicityMemantineAnesthesiaInternal medicineReceptorDiseaseTreatment of Major DepressionAnesthesia and Neurotoxicity ResearchAnesthesia and Sedative Agents
A comparison of the pharmacokinetics and NMDAR antagonism-associated neurotoxicity of ketamine, (2R,6R)-hydroxynorketamine and MK-801 | Litcius