Litcius/Paper detail

Fasting and Non-Fasting Triglycerides and Risk of Cardiovascular Events in Diabetic Patients Under Statin Therapy

Hayato Tada, Akihiro Nomura, Kenichi Yoshimura, Hiroshi Itoh, Issei Komuro, Masakazu Yamagishi, Masayuki Takamura, Masa‐aki Kawashiri

2020Circulation Journal35 citationsDOIOpen Access PDF

Abstract

BACKGROUND: Few data specifically investigate associations between fasting/non-fasting triglycerides (TG) and cardiovascular (CV) events under statin therapy among Japanese diabetic patients. METHODS AND RESULTS: ). Comparing the top quartile with the bottom quartile of non-fasting TG, adjusted HR significantly increased 5.18 (95% CI: 1.38-18.3, P=0.014) for MACE, and 2.40 (95% CI: 1.11-4.75, P=0.021) for CVD, while adjusted HR did not change when divided into quartile of fasting TG. CONCLUSIONS: Non-fasting TG could be considered as a substitute for fasting TG as a risk stratification for future CV events among Japanese diabetic patients.

Topics & Concepts

MedicineInternal medicineStatinDiabetes mellitusEndocrinologyCholesterolDiabetes, Cardiovascular Risks, and LipoproteinsDietary Effects on HealthLipoproteins and Cardiovascular Health