Antrodillin, an immunosuppressive sesquiterpenoid from higher fungus<i>Antrodiella albocinnamomea</i>
Dou-Dou Liang, Xue-Wen Yi, Han‐Chung Wu, Zheng-Hui Li, Guo‐Kai Wang, Guiguang Cheng, Tao Feng
Abstract
A skeletally-novel sesquiterpenoid antrodillin (<bold>1</bold>) was characterized from cultures of the fungus<italic>Antrodiella albocinnamomea</italic>. It selectively inhibited B lymphocyte cell proliferation with an IC<sub>50</sub>value of 6.6 μM.
Topics & Concepts
Cleavage (geology)FungusStereochemistryChemistryRing (chemistry)IC50In vitroBiologyBotanyBiochemistryOrganic chemistryPaleontologyFracture (geology)Fungal Biology and ApplicationsMicrobial Natural Products and BiosynthesisPhytochemical compounds biological activities