Henoch‐Schönlein purpura: Another COVID‐19 complication
Georges El Hasbani, Alì Taher, Ali Jawad, Imad Uthman
Abstract
Whether affecting children or adults, SARS-CoV-2 infection (COVID-19) can have multi-organ involvement mediated by an inflammatory cascade. Immunoglobulin A (IgA) is one of the key components of the inflammatory cascade that can lead to endothelial injury and inflammation. IgA vasculitis or Henoch-Schönlein purpura (HSP) has been rarely reported in the context of COVID-19. In this report, we highlight a case of HSP occurring 2 days after diagnosis of COVID-19 in a 16-year-old boy, who presented with palpable purpura of the lower extremities and buttocks, diffuse abdominal pain, hemoptysis, and hematochezia. He was treated with oral prednisolone with rapid clinical improvement.
Topics & Concepts
MedicineCoronavirus disease 2019 (COVID-19)Purpura (gastropod)ComplicationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakHenoch-Schonlein purpuraDermatologyCoronavirus InfectionsVirologyVasculitisSurgeryInternal medicineOutbreakInfectious disease (medical specialty)BiologyEcologyDiseaseVasculitis and related conditionsInflammasome and immune disordersKawasaki Disease and Coronary Complications