Visible light induced cooperative carbonylation and (hetero)aryl migration: synthesis of multi-carbonyl compounds
Hefei Yang, Yuanrui Wang, Le‐Cheng Wang, Xiao‐Feng Wu
Abstract
Carbonylative transformation represents one of the most straightforward procedures for the synthesis of carbonyl-containing compounds. However, the carbonylative procedure toward 1,4-diketones is still limited which are key moieties with potent applications in various areas. Herein, we report a new strategy for the synthesis of multi-carbonyl compounds containing a 1,4-diketone skeleton through remote heteroaryl migration of traditionally restricted 1,3-migratory substrates utilizing carbon monoxide (CO) as the C1 synthon and diazonium compounds as the starting material.
Topics & Concepts
CarbonylationArylCombinatorial chemistryChemistryVisible spectrumPhotochemistryCatalysisOrganic chemistryMaterials scienceCarbon monoxideAlkylOptoelectronicsCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsCyclopropane Reaction Mechanisms