Litcius/Paper detail

Changes in the Gut Microbiota of Rats in High-Altitude Hypoxic Environments

Xue Bai, Guiqin Liu, Jianxin Yang, Junbo Zhu, Qian Wang, Yang Zhou, Wenqi Gu, Linli La, Xiangyang Li

2022Microbiology Spectrum47 citationsDOIOpen Access PDF

Abstract

In this study, we investigated the effects of high-altitude hypoxic environments with low oxygen levels on the gut microbiota characteristics of rats. We observed that high-altitude hypoxia is an important environmental factor that can affect gut microbiota structure and diversity, thereby affecting homeostasis in the host intestinal environment. These findings provide a basis for further studies on disease initiation and development, as well as drug metabolism, in high-altitude hypoxic environments.

Topics & Concepts

Effects of high altitude on humansAltitude (triangle)Gut floraHypoxia (environmental)BiologyPhysiologyChemistryImmunologyOxygenAnatomyMathematicsOrganic chemistryGeometryDiet and metabolism studiesHigh Altitude and HypoxiaGut microbiota and health