Astragalin ameliorates renal injury in diabetic mice by modulating mitochondrial quality control via AMPK-dependent PGC1α pathway
Mengyao Sun, Hui-jing Ye, Zheng Chen, Zijie Jin, Yan Yuan, Hongbo Weng
Topics & Concepts
AMPKAldose reductaseOxidative stressEndocrinologyMitochondrial biogenesisInternal medicineDiabetes mellitusDiabetic cardiomyopathyDownregulation and upregulationMedicineMitochondrionPharmacologyChemistryProtein kinase ABiochemistryEnzymeHeart failureGeneCardiomyopathyAldose Reductase and TaurineHeme Oxygenase-1 and Carbon MonoxideNeonatal Health and Biochemistry