Drug delivery with a pH-sensitive star-like dextran-graft polyacrylamide copolymer
Anna Grebinyk, Svitlana Prylutska, Sergii Grebinyk, Станіслав Пономаренко, Pavlo Virych, Vasyl Chumachenko, Nataliya Kutsevol, Yu. І. Prylutskyy, Uwe Ritter, Marcus Frohme
Abstract
-PAAan nanoparticle allows not only to realize pH-triggered drug release but also to potentiate its cytotoxic, prooxidant and proapoptotic effects against lung carcinoma cells.
Topics & Concepts
CopolymerDextranStar (game theory)DrugPolyacrylamideDrug deliveryPolymer chemistryChemistryMaterials scienceMedicinePharmacologyChromatographyPolymerNanotechnologyOrganic chemistryPhysicsAstrophysicsNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsGraphene and Nanomaterials Applications