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Translational control of gene function through optically regulated nucleic acids

Kristie Darrah, Alexander Deiters

2021Chemical Society Reviews36 citationsDOIOpen Access PDF

Abstract

models. In this review, we discuss the different optochemical approaches used to generate photoresponsive nucleic acids that activate and deactivate gene expression and function at the translational level.

Topics & Concepts

Nucleic acidFunction (biology)GeneComputational biologyChemistryBiologyGeneticsBiochemistryPhotochromic and Fluorescence ChemistryAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid Chemistry
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