Unexpected CK2β-antagonistic functionality of bisubstrate inhibitors targeting protein kinase CK2
Markus Pietsch, Kaido Viht, Alexander Schnitzler, Ramesh Ekambaram, Michaela Steinkrüger, Erki Enkvist, Christian Nienberg, Anna Nickelsen, Miriam Lauwers, Joachim Jose, Asko Uri, Karsten Niefind
Topics & Concepts
ChemistryCasein kinase 2Arc (geometry)KinaseProtein kinase ABiochemistryBiophysicsCyclin-dependent kinase 2BiologyMathematicsGeometryProtein Kinase Regulation and GTPase SignalingEnzyme Structure and FunctionProtein Structure and Dynamics