A general protocol for stereoselective construction of enaminyl sulfonyl fluorides
Liu-Yang Chen, K.P. Rakesh, Hua‐Li Qin
Abstract
A simple, efficient, and mild reaction of 2-chloroprop-2-ene-1-sulfonyl fluoride (CESF) with amines was developed, affording a variety of highly functionalized enaminyl sulfonyl fluorides in good to excellent yields (56–96%).
Topics & Concepts
SulfonylChemistryStereoselectivityFluorideOrganic chemistryReaction conditionsCombinatorial chemistryMedicinal chemistryCatalysisInorganic chemistryAlkylSynthesis and Catalytic ReactionsSulfur-Based Synthesis TechniquesClick Chemistry and Applications