The impact of prebiotic fructooligosaccharides on gut dysbiosis and inflammation in obesity and diabetes related kidney disease
Nattavadee Pengrattanachot, Laongdao Thongnak, Anusorn Lungkaphin
Abstract
the exacerbation of the inflammatory response and its association with gut dysbiosis. In addition, the role of fructooligosaccharides (FOS), a source of prebiotic widely available commercially, on the improvement of gut dysbiosis and attenuation of inflammation on obese and diabetic conditions has been reviewed. The evidence confirms that FOS supplementation could improve the pathological changes associated with obesity and diabetes related kidney disease, however, knowledge concerning the mechanisms involved is still limited and needs further elucidation.
Topics & Concepts
DysbiosisPrebioticDiabetes mellitusInflammationExacerbationGut floraObesityMedicineType 2 diabetesDiseaseSystemic inflammationInternal medicineImmunologyEndocrinologyBiologyGeneticsDiet, Metabolism, and DiseaseDiet and metabolism studiesMicrobial Metabolites in Food Biotechnology