Design, synthesis and anti-tumor activity of novel benzothiophenonaphthalimide derivatives targeting mitochondrial DNA (mtDNA) G-quadruplex
Qiong Huang, Xiao Wang, An Chen, Hua Zhang, Qimeng Yu, Chenfeng Shen, Annoor Awadasseid, Xiaoyin Zhao, Xuqiong Xiong, Yanling Wu, Wen Zhang
Topics & Concepts
ApoptosisIn vivoMitochondrionAutophagyChemistryIn vitroReactive oxygen speciesCell cycleCell cycle checkpointMechanism of actionCancer cellMolecular biologyBiochemistryCell biologyBiologyCancerGeneticsDNA and Nucleic Acid ChemistryAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery