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Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling

A. Goepfert, Sylvie Lehmann, Jutta Blank, Frank Kolbinger, Jean‐Michel Rondeau

2020Immunity76 citationsDOIOpen Access PDF

Topics & Concepts

BiologySignal transductionCell biologyCytokineInterleukin 17Immune systemReceptorExtracellularInterleukinInterleukin 22Innate immune systemImmunologyGeneticsPsoriasis: Treatment and PathogenesisWhipple's Disease and InterleukinsIL-33, ST2, and ILC Pathways