The colonic polyphenol catabolite dihydroferulic acid (DHFA) regulates macrophages activated by oxidized LDL, 7-ketocholesterol, and LPS switching from pro- to anti-inflammatory mediators
Óscar J. Lara-Guzmán, Ángela Arango-González, Diego A. Rivera, Katalina Muñoz-Durango, Jelver Sierra
Abstract
Macrophage activation plays a central role in the development of atherosclerotic plaques.
Topics & Concepts
Catabolite repressionChemistryCell biologyInflammationBiochemistryInternal medicineMedicineBiologyGeneMutantCholesterol and Lipid MetabolismPhytochemicals and Antioxidant ActivitiesGenomics, phytochemicals, and oxidative stress