A NH2-Cu-MOF for promising antibacterial application
Zhenxi Li, Jing Cheng, Zhixin Xie, Linlin Chen
Abstract
A copper-based metal-organic framework named NH 2 -Cu-MOF has been synthesized and utilized as an effective broad-spectrum antimicrobial material in this article. The obtained NH 2 -Cu-MOF exhibits satisfying antibacterial activity against both gram-positive bacteria ( S. aureus and S. epidermidis ) and gram-negative bacteria ( E. coli and K. peneumoniae ). Additionally, the biocompatibility of this NH 2 -Cu-MOF has been validated through animal studies, showing no significant adverse effects, thereby confirming its high biocompatibility. These findings prove that NH 2 -Cu-MOF has positive effects upon the treatment of bacteria-infected wounds, which holds great potential to be applied in biochemistry field.