Comparison of open and closed hyperthermic intraperitoneal chemotherapy: Results from the United States hyperthermic intraperitoneal chemotherapy collaborative
Jennifer L. Leiting, Jordan M. Cloyd, Ahmed Ahmed, Keith F. Fournier, Andrew J. Lee, Sophie Dessureault, Seth Felder, Jula Veerapong, Joel Baumgartner, Callisia N. Clarke, Harveshp Mogal, Charles A. Staley, Mohammad Y. Zaidi, Sameer H. Patel, Syed A. Ahmad, Ryan J. Hendrix, Laura Lambert, Daniel E. Abbott, Courtney Pokrzywa, Mustafa Raoof, Christopher J. LaRocca, Fabian M. Johnston, Jonathan B. Greer, Travis E. Grotz
Abstract
BACKGROUND: Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal carcinomatosis can be performed in two ways: Open or closed abdominal technique. AIM: To evaluate the impact of HIPEC method on post-operative and long-term survival outcomes. METHODS: closed HIPEC. RESULTS: = 0.05) in the entire cohort. These findings remained consistent in the appendiceal and the colorectal subgroups. CONCLUSION: In this multi-institutional analysis, the HIPEC method was not independently associated with relevant post-operative or long-term outcomes. HIPEC technique may be left to the discretion of the operating surgeon.