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Outcome of COVID‐19 in multiple myeloma patients in relation to treatment

Katharina H. Susek, Charlotte Gran, Hans‐Gustaf Ljunggren, Evren Alici, Hareth Nahi

2020European Journal Of Haematology21 citationsDOIOpen Access PDF

Abstract

COVID-19 has emerged as a global pandemic. Cancer patients have been reported to be at higher risk for adverse outcome of COVID-19. Studies are ongoing to decipher the risk factors and risk groups among cancer patients as well as strategies to refine treatment approaches. Here, we report eight patients with multiple myeloma that underwent immunomodulatory therapies with daratumumab or lenalidomide-based combination treatments and one patient with smoldering multiple myeloma, all of which presented with symptomatic COVID-19. We report that patients that succumbed to COVID-19 presented with either progressive tumor disease under daratumumab treatment or were in remission under lenalidomide-dexamethasone treatment.

Topics & Concepts

DaratumumabLenalidomideMultiple myelomaMedicineInternal medicineDexamethasoneCoronavirus disease 2019 (COVID-19)OncologyDiseaseAdverse effectPandemicIntensive care medicineInfectious disease (medical specialty)Multiple Myeloma Research and TreatmentsCOVID-19 and healthcare impactsCOVID-19 Clinical Research Studies
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