Blending with Poly(<scp>l</scp>-lactic acid) Improves the Printability of Poly(<scp>l</scp>-lactide-<i>co</i>-caprolactone) and Enhances the Potential Application in Cartilage Tissue Engineering
Ruiping Duan, Yimeng Wang, Yiyun Zhang, Ziqiang Wang, Fuchong Du, Bo Du, Danning Su, Lingrong Liu, Xuemin Li, Qiqing Zhang
Abstract
seeded chondrocytes accompanied by upregulated expression of SOX9 than the PLCL scaffold. Taken together, these results demonstrate that blending with PLLA improves the printability of PLCL and enhances its potential application, particularly PLCL/PLLA scaffolds with a low ratio of PLLA, in cartilage tissue engineering.
Topics & Concepts
Materials scienceScaffoldCaprolactoneViscoelasticityTissue engineeringChondrogenesisCartilagePolylactic acidComposite materialBiodegradable polymerLactideBiomedical engineeringPolymerPolymerizationAnatomyMedicineBone Tissue Engineering Materialsbiodegradable polymer synthesis and propertiesAdditive Manufacturing and 3D Printing Technologies