Dual targeting of FR+CD44 overexpressing tumors by self-assembled nanoparticles quantitatively conjugating folic acid-hyaluronic acid to the GSH-sensitively modified podophyllotoxin
Chaozheng Zhang, Yao Chen, Yi Y. Zuo, Maolin Wang, Hongyu Chen, Chuanqi Wang, Yuening Cao, Yingjie Zeng, Ying Chen, Tingting Zhang, Xian Ge, Xiujun Cao, Yilan Liu, Hongbin Cheng, Yun Deng, Jun Lü
Topics & Concepts
Hyaluronic acidFolic acidPodophyllotoxinChemistryCD44NanoparticleGlutathioneBiochemistryBiophysicsCombinatorial chemistryPharmacologyNanotechnologyStereochemistryMaterials scienceMedicineBiologyInternal medicineIn vitroEnzymeAnatomyNanoparticle-Based Drug DeliveryCancer, Hypoxia, and MetabolismGlycosylation and Glycoproteins Research