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Validation of Food Compass with a healthy diet, cardiometabolic health, and mortality among U.S. adults, 1999–2018

Meghan O’Hearn, Joshua Erndt‐Marino, Suzannah Gerber, Brianna N. Lauren, Christina D. Economos, John B. Wong, Jeffrey B. Blumberg, Dariush Mozaffarian

2022Nature Communications36 citationsDOIOpen Access PDF

Abstract

Abstract The Food Compass is a nutrient profiling system (NPS) to characterize the healthfulness of diverse foods, beverages and meals. In a nationally representative cohort of 47,999 U.S. adults, we validated a person’s individual Food Compass Score (i.FCS), ranging from 1 (least healthful) to 100 (most healthful) based on cumulative scores of items consumed, against: (a) the Healthy Eating Index (HEI) 2015; (b) clinical risk factors and health conditions; and (c) all-cause mortality. Nationally, the mean (SD) of i.FCS was 35.5 (10.9). i.FCS correlated highly with HEI-2015 (R = 0.81). After multivariable-adjustment, each one SD (10.9 point) higher i.FCS associated with more favorable BMI (−0.60 kg/m 2 [−0.70,−0.51]), systolic blood pressure (−0.69 mmHg [−0.91,−0.48]), diastolic blood pressure (−0.49 mmHg [−0.66,−0.32]), LDL-C (−2.01 mg/dl [−2.63,−1.40]), HDL-C (1.65 mg/d [1.44,1.85]), HbA1c (−0.02% [−0.03,−0.01]), and fasting plasma glucose (−0.44 mg/dL [−0.74,−0.15]) ; lower prevalence of metabolic syndrome (OR = 0.85 [0.82,0.88]), CVD (0.92 [0.88,0.96]), cancer (0.95 [0.91,0.99]), and lung disease (0.92 [0.88,0.96]); and higher prevalence of optimal cardiometabolic health (1.24 [1.16,1.32]). i.FCS also associated with lower all-cause mortality (HR = 0.93 [0.89,0.96]). Findings were similar by age, sex, race/ethnicity, education, income, and BMI. These findings support validity of Food Compass as a tool to guide public health and private sector strategies to identify and encourage healthier eating.

Topics & Concepts

MedicineBlood pressureCohortInternal medicineWhole grainsDiastoleFood groupFood scienceEnvironmental healthBiologyObesity, Physical Activity, DietConsumer Attitudes and Food LabelingNutritional Studies and Diet
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