Conformation-dependent charge transport through short peptides
Davide Stefani, Cunlan Guo, Luca Ornago, Damien Cabosart, Maria El Abbassi, Mordechai Sheves, David Cahen, Herre S. J. van der Zant
Abstract
being the conductance quantum, whereas slightly longer, more flexible peptides also show plateaus at higher values. Fully stretched peptide chains exhibit conductance values that are of the same order as that of alkane chains of similar length. The measurements show that in the case of short peptides, different compositions and molecular lengths offer a wide range of junction conformations. Such information is crucial to understand mechanism(s) of charge transport in and across peptide-based biomolecules.
Topics & Concepts
Conformational isomerismCharge (physics)PeptideElectron transport chainMoleculeChemical physicsBiophysicsNanotechnologyMaterials scienceChemistryPhysicsBiochemistryBiologyOrganic chemistryQuantum mechanicsMolecular Junctions and NanostructuresForce Microscopy Techniques and ApplicationsAdvanced biosensing and bioanalysis techniques