Identification of Reduced ERAP2 Expression and a Novel HLA Allele as Components of a Risk Score for Susceptibility to Liver Injury Due to Amoxicillin-Clavulanate
Paola Nicoletti, Andrew Dellinger, Yi‐Ju Li, Huiman X. Barnhart, Naga Chalasani, Robert J. Fontana, Joseph A. Odin, José Serrano, Andrew Stolz, Amy S. Etheridge, Federico Innocenti, Olivier Govaere, Jane I. Grove, Camilla Stephens, Guruprasad P. Aithal, Raúl J. Andrade, Einar S. Björnsson, Ann K. Daly, M. Isabel Lucena, Paul B. Watkins
Topics & Concepts
Odds ratioInternal medicineGenome-wide association studySingle-nucleotide polymorphismPopulationHuman leukocyte antigenMedicineBiologyOncologyImmunologyGeneticsGenotypeGeneAntigenEnvironmental healthDrug-Induced Hepatotoxicity and ProtectionPharmacogenetics and Drug MetabolismPharmacovigilance and Adverse Drug Reactions