Litcius/Paper detail

Recent Progress in the Asymmetric Syntheses of α‐Heterofunctionalized (Masked) α‐ and β‐Amino Acid Derivatives

Isabella Eder, Victoria Haider, Paul Zebrowski, Mario Waser

2020European Journal of Organic Chemistry31 citationsDOIOpen Access PDF

Abstract

The asymmetric synthesis of α‐heterofunctionalized α‐ and β‐amino acid derivatives has been a heavily investigated topic over the last years, benefiting from the development of novel catalysis concepts as well as from the introduction of suited new precursor entities. Within this short review, we wish to give an illustrative overview of the most successfully applied concepts to access these targets, like asymmetric α‐heterofunctionalizations or asymmetric C–C‐bond forming reactions of already heterofunctionalized precursors.

Topics & Concepts

ChemistryEnantioselective synthesisCombinatorial chemistryAmino acidOrganocatalysisCatalysisOrganic chemistryNanotechnologyBiochemistryMaterials scienceAsymmetric Synthesis and CatalysisChemical Synthesis and AnalysisAsymmetric Hydrogenation and Catalysis