EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma
Tianfu Yu, Fengqi Zhou, Wei Tian, Ran Xu, Binbin Wang, Ailiang Zeng, Zhijun Zhou, Min Li, Yingyi Wang, Junxia Zhang
Topics & Concepts
EZH2BiologyTemozolomideCancer researchWnt signaling pathwayPRC2RadioresistanceStem cellHistone methyltransferaseGliomaHistoneCell biologySignal transductionGeneticsCell cultureGeneEpigenetics and DNA MethylationCancer-related molecular mechanisms researchGenomics and Chromatin Dynamics