Antioxidant, Anti-inflammatory, and Analgesic Activities of Alcoholic Extracts of <i>Ephedra nebrodensis</i> From Eastern Algeria
Meriem Hamoudi, Djouher Amroun, Abderrahmane Baghiani, Seddik Khennouf, Saliha Dahamna
Abstract
Objectives: in mice. Materials and Methods: anti-inflammatory effect of the extracts (200 and 400 mg/kg). Finally, the analgesic activity of the extracts (200 and 400 mg/kg) was determined by the acetic acid-induced torsion test. Results: and could reduce ear edema by 70.37%±2.00% and 72.22%±1.94%, respectively. The HM extract (72.51%±2.43%) demonstrates greater pain inhibitory effects than HE (70.76%±2.58%). Conclusion: The hydro-alcoholic extracts of E. nebrodensis produce antioxidant, anti-inflammatory, and analgesic effects. These results confirm the traditional use of the herb in the treatment of various diseases.
Topics & Concepts
AntioxidantChemistryAnalgesicIn vivoTraditional medicinePharmacologyAnti-inflammatoryCrotonCroton oilBiochemistryMedicineInflammationBiologyImmunologyBiotechnologyPharmacology and Obesity TreatmentEssential Oils and Antimicrobial ActivityChemical synthesis and alkaloids