CD44v6-targeted CAR T-cells specifically eliminate CD44 isoform 6 expressing head/neck squamous cell carcinoma cells
Corinna Haist, Elena Schulte, Nina Bartels, Arthur Bister, Zoe Poschinski, Tabea C. Ibach, Katja Geipel, Constanze Wiek, Martin Wagenmann, Cornelia Monzel, Kathrin Scheckenbach, Helmut Hanenberg
Topics & Concepts
Chimeric antigen receptorHead and neck squamous-cell carcinomaCancer researchCD44ImmunotherapyAntigenCancerImmune systemMetastasisBiologyMedicineImmunologyCellHead and neck cancerInternal medicineGeneticsCAR-T cell therapy researchImmunotherapy and Immune ResponsesVirus-based gene therapy research