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Modular, efficient and constant-memory single-cell RNA-seq preprocessing

Páll Melsted, A. Sina Booeshaghi, Lauren Liu, Fan Gao, Lambda Lu, Kyung Hoi Min, Eduardo da Veiga Beltrame, Kristján Eldjárn Hjörleifsson, Jase Gehring, Lior Pachter

2021Nature Biotechnology498 citationsDOI

Topics & Concepts

Modular designConstant (computer programming)RNA-SeqPreprocessorComputer scienceComputational biologyRNABiologyGeneticsGene expressionTranscriptomeProgramming languageGeneSingle-cell and spatial transcriptomicsExtracellular vesicles in diseaseCRISPR and Genetic Engineering
Modular, efficient and constant-memory single-cell RNA-seq preprocessing | Litcius