Autophagy deficiency abolishes liver mitochondrial DNA segregation
Katiane Tostes, Angélica Camargo dos Santos, Lindomar de Oliveira Alves, Luiz Roberto Grassmann Bechara, Rachel Marascalchi, Carolina H. Macabelli, Mateus P. Grejo, William T. Festuccia, Roberta A. Gottlieb, Julio Cesar Batista Ferreira, Marcos Roberto Chiaratti
Abstract
: transcription factor B2, mitochondrial; TOMM20: translocase of outer mitochondrial membrane 20; UQCRC2: ubiquinol cytochrome c reductase core protein 2; WT: wild-type.
Topics & Concepts
HeteroplasmyMitochondrial DNABiologyGeneticsMitochondrionMutantHuman mitochondrial geneticsMutationMolecular biologyGeneMitochondrial Function and PathologyAutophagy in Disease and TherapyMetabolism and Genetic Disorders