Antitumor efficacy of oncolytic HSV-1 expressing cytosine deaminase is synergistically enhanced by DPD down-regulation and EMT inhibition in uveal melanoma xenograft
Sisi Liu, Junwen Zhang, Sheng Fang, Xiaodong Su, Qing Zhang, Gui‐Dong Zhu, Li Zhu, Mingwei Zhao, Fusheng Liu
Topics & Concepts
Oncolytic virusCancer researchHerpes simplex virusIn vivoDihydropyrimidine dehydrogenaseMelanomaBiologyMedicineVirusImmunologyChemotherapyFluorouracilInternal medicineTumor cellsBiotechnologyThymidylate synthaseVirus-based gene therapy researchImmunotherapy and Immune ResponsesOcular Oncology and Treatments