Acute SARS-CoV-2 infection is associated with an increased abundance of bacterial pathogens, including Pseudomonas aeruginosa in the nose
Nicholas S. Rhoades, Amanda N. Pinski, Alisha N. Monsibais, Allen Jankeel, Brianna M. Doratt, Isaac R. Cinco, Izabela Coimbra Ibraim, Ilhem Messaoudi
Abstract
patients, indicative of an antiviral innate immune response and neuronal damage. These data suggest that the inflammatory response caused by SARS-CoV-2 infection is associated with an increased abundance of bacterial pathogens in the nasal cavity that could contribute to increased incidence of secondary bacterial infections.
Topics & Concepts
Pseudomonas aeruginosaMicrobiomeImmunologyBiologyPathogenesisImmune systemSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MicrobiologyNoseCoronavirusVirologyIncidence (geometry)DiseaseCoronavirus disease 2019 (COVID-19)MedicineBacteriaInfectious disease (medical specialty)BioinformaticsPathologyAnatomyOpticsGeneticsPhysicsSARS-CoV-2 and COVID-19 ResearchOlfactory and Sensory Function StudiesSinusitis and nasal conditions