Electrocatalytic three-component synthesis of 4-halopyrazoles with sodium halide as the halogen source
Jinyang Chen, Hongxia Li, Si‐Yu Mu, Hai‐Yang Song, Zhilin Wu, Tianbao Yang, Jun Jiang, Wei‐Min He
Abstract
The first example of the electrocatalytic multicomponent synthesis of 4-chloro/bromo/iodopyrazoles from hydrazines, acetylacetones and sodium halides under chemical oxidant- and external electrolyte-free conditions has been developed.
Topics & Concepts
ChemistryHalogenationHalideHalogenReagentElectrolyteSodiumIonic bondingInorganic chemistryOrganic chemistryCombinatorial chemistryIonElectrodeAlkylPhysical chemistryOxidative Organic Chemistry ReactionsRadical Photochemical ReactionsVanadium and Halogenation Chemistry