Treatment Strategies and Related Outcomes for Brain Arteriovenous Malformations in Children: A Systematic Review and Meta-Analysis
Parneyan Pezeshkpour, Adam A. Dmytriw, Kevin Phan, Manohar Shroff, Peter Dirks, Abhaya V. Kulkarni, Prakash Muthusami
Abstract
Multimodality treatments for pediatric bAVM had lower mortality and complication rates than individual treatments. However, there is a lack of evidence for long-term outcomes. The mortality rate was highest in conservatively managed patients (i.e., observation only). Further research directly comparing different treatment modalities for recurrence and complications is warranted. Gathering data prospectively through multiinstitutional registries will be key to provide strong evidence.
Topics & Concepts
MedicineArteriovenous malformationPoisson regressionRadiosurgeryMeta-analysisComplicationEmbolizationMortality rateMEDLINEIntracranial Arteriovenous MalformationsSurgeryPediatricsInternal medicinePopulationRadiation therapyCerebral angiographyEnvironmental healthLawPolitical scienceAngiographyVascular Malformations Diagnosis and TreatmentIntracranial Aneurysms: Treatment and ComplicationsMeningioma and schwannoma management