Targeted delivery of lopinavir to HIV reservoirs in the mesenteric lymphatic system by lipophilic ester prodrug approach
Chaolong Qin, Yenju Chu, Wanshan Feng, Christophe Fromont, Sijia He, Joseph Ali, Jong Bong Lee, Atheer Zgair, Mattia Berton, Sara Bettonte, Ruiling Liu, Lei Yang, Teerapong Monmaturapoj, Concepción Medrano‐Padial, Allen Alonso Rodríguez Ugalde, Daria Vetrugno, Shi Ying Ee, Charles Sheriston, Yuntao Wu, Michael J. Stocks, Peter M. Fischer, Pavel Gershkovich
Topics & Concepts
ProdrugLymphIn vivoPharmacologyPharmacokineticsOral administrationMesenteric lymph nodesChylomicronLymphatic systemEx vivoChemistryMedicineIn vitroBiochemistrySpleenCholesterolBiologyImmunologyPathologyLipoproteinVery low-density lipoproteinBiotechnologyHIV Research and TreatmentHIV/AIDS Research and InterventionsHIV-related health complications and treatments